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. 2021 Jan 11;11:575762. doi: 10.3389/fgene.2020.575762

TABLE 2.

Correlation analysis between candidate hub genes and immune cells in the TIMER2.0 database.

Hub genes Purity
B cell
CD8+ T cell
CD4+ T cell
Macrophage
Neutrophil
DC
COR P COR P COR P COR P COR P COR P COR P
TOP2A 0.186 ** 0.410 *** 0.150 * 0.247 *** 0.372 *** 0.239 *** 0.531 ***
CCNB2 0.151 * 0.433 *** 0.124 0.021 0.239 *** 0.321 *** 0.164 * 0.547 ***
PRC1 0.191 ** 0.426 *** 0.142 * 0.247 *** 0.384 *** 0.217 *** 0.526 ***
RACGAP1 0.179 ** 0.382 *** 0.141 * 0.212 *** 0.362 *** 0.288 *** 0.515 ***
AURKA 0.148 * 0.451 *** 0.058 0.280 0.157 * 0.262 *** 0.096 0.076 0.466 ***
CDKN3 0.183 ** 0.403 *** 0.123 0.022 0.188 ** 0.311 *** 0.128 0.018 0.449 ***
NUSAP1 0.170 * 0.459 *** 0.147 * 0.260 *** 0.382 *** 0.183 ** 0.545 ***
CDCA5 0.177 ** 0.435 *** 0.093 0.085 0.250 *** 0.339 *** 0.131 0.015 0.548 ***
ASPM 0.169 * 0.364 *** 0.148 * 0.210 *** 0.294 *** 0.203 ** 0.453 ***
NCAPG 0.146 * 0.407 *** 0.095 0.078 0.203 ** 0.314 *** 0.177 ** 0.509 ***

COR, correlation coefficient; DC, dendritic cell; **, p < 0.0001; **, p < 0.001; *, p < 0.01.