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. 2021 Jan 18;22(2):905. doi: 10.3390/ijms22020905

Table 2.

Alpha-smooth muscle actin staining scores of renal biopsy tissues sampled repeatedly from 6 PSAGN patients and their characteristics.

Patient Age (Years) Acute Phase: Duration between Onset to First Biopsy (Days) Convalescent Phase: Duration between Onset to Second Biopsy (Years) Glomerular Staining Score Interstitial Staining Score
First Biopsy Second Biopsy First Biopsy Second Biopsy
Progression into CKD (n = 3) 39.3 ± 6.0 19.7 ± 9.9 3.0 ± 1.0 2.7 ± 1.2 0.7 ± 0.6 3.7 ± 0.6 3.0 ± 1.0
Cured
(n = 3)
35.7 ± 7.8 23.3 ± 12.1 5.1 ± 4.5 3.0 ± 1.0 0.7 ± 0.6 2.7 ± 0.6 1.7 ± 0.6

PSAGN: poststreptococcal acute glomerulonephritis; CKD: chronic kidney disease. Data are expressed as the mean ± SD. Sections stained for α-SMA as described in Figure 4 were evaluated as follows. Glomerular staining intensities were semiquantitatively graded as 0 to 4, as previously reported by Alpers et al. [48], whereas interstitial staining intensities were graded semiquantitatively as 1 to 4 using the following scale: 1 = positive area < 10%; 2 = 10% to 20%; 3 = 20% to 30%; 4 ≥ 30%.