Table 1.
Baseline characteristics of the entire patient population and stratified into age groups.
| Characteristics | Total | Age Group | p-Value | |
|---|---|---|---|---|
| >= 65 (A) | < 65 (B) | |||
| N | 807 | 315 | 492 | |
| Age (years) Mean/median Range |
60.6/61.0 29.8–85.9 |
71.2/72.1 65–85.9 |
53.6/55.8 25.3–64.9 |
|
| Gender Female (%) Male (%) |
51.05 48.95 |
45.1 54.9 |
54.9 45.1 |
0.0007 |
| Primary cancer sites (%) Lung Breast Melanoma GI tract Kidney Others |
41.5 15.4 14.6 9.2 3.7 15.6 |
44.4 12.4 11.4 11.4 5.1 15.3 |
39.6 17.9 16.7 7.7 2.9 15.2 |
0.001 |
| Presurgical Karnofsky performance status Median Range |
80 40–100 |
80 40–100 |
80 40–100 |
0.128 |
| Postsurgical Karnofsky performance status Median Range |
90 50–100 |
90 50–100 |
90 60–100 |
0.0002 |
| Systemic disease control Yes (%) No (%) |
42.8 57.2 |
49.3 50.7 |
38.5 61.5 |
0.042 |
| Metastasis status (%) Solitary Singular Multiple |
22.9 38.9 38.2 |
30.5 38.4 31.1 |
18.1 39.2 42.7 |
0.0001 |
| Number of metastases Mean/median Range |
2.1/1 1–19 |
1.8/1 1–19 |
2.3/1 1–17 |
0.002 |
| Metastasis timing (%) Synchronous Metachronous |
36.4 63.6 |
37.5 62.5 |
35.8 64.2 |
0.327 |
| Comorbidity score Mean/median Range |
3.5/3.0 0–9 |
4.3/4.0 1–9 |
2.9/3.0 0–9 |
0.0001 |
| Interval between tumor diagnosis to BM Mean/median Range |
30.4/11.1 0–139 |
28.3/10.0 0–132 |
31.74/12.9 0–139 |
0.392 |
| Postsurgical radiation (%) | 86.6 | 80.0 | 87.6 | 0.009 |
| Postsurgical systemic treatment (%) | 49.2 | 45.1 | 59.9 | 0.0001 |
| Surgical morbidity (%) | 10.8 | 10.9 | 10.7 | 0.992 |
| Surgical mortality | 4.2 | 6.4 | 2.9 | 0.016 |