Table 2.
Median and mean concentrations of WBC DIFF counts in NSG male and female mice measured with a IDEXX ProCyte Dx analyzer and by a microscopic count. (data for C57/BL6 mice are given for comparison)
| ANOVA p |
|||||||
| Variable (unit) | n | Method | Method | Gender | Median (range) | Mean (SD) | C57 BL/6J39 Median (range) |
| Neutrophils (109/L) | 17m+16fa | P/M | 0.177 | <0.001 | 0.81 (0.44–2.05) | 0.97 (0.45) | 0.76 (0.38–2.92) |
| 17m | 0.65 (0.44–0.89) | 0.65 (0.14) | |||||
| 16fa | 1.30 (0.62–2.05) | 1.30 (0.42) | |||||
| Lymphocytes (109/L) | 17m+16fb | P | <0.001 | 0.014 | 0.30 (0.14–0.57) | 0.30 (0.10) | 5.14 (2.27–9.76) |
| 17m | 0.26 (0.14–0.35) | 0.26 (0.07) | |||||
| 16fb | 0.35 (0.17–0.57) | 0.34 (0.11) | |||||
| 17m+16fc | M | 0.844 | 0.02 (0.00–0.12) | 0.03 (0.03) | |||
| Monocytes (109/L) | 17m+16fd | P | <0.001 | 0.132 | 0.01 (0.00–0.005) | 0.02 (0.01) | 0.02 (0.01–0.09) |
| 17m+16fe | M | 0.731 | 0.17 (0.06–0.42) | 0.19 (0.09) | |||
| Eosinophils (109/L) | 17m+16ff | P/M | 0.196 | 0.052 | 0.02 (0.01–0.05) | 0.02 (0.01) | 0.11 (0.05–0.22) |
P: ProCyte Dx analyzer; M: Microscopic count; m: males; f: females; SD: standard deviation; outliers deleted: a: 4.49; 2.98; 3.85; b: 0.53; 0.45; 0.41; c: 0.05; 0.18; 0.00; d: 0.1; 0.03; 0.07; e: 0.1; 0.18; 0.26; f: 0.02; 0.03; 0.02. Corresponding reference intervals are given as supplementary tables.