Table 2.
Comparisons of withdrawal thresholds recorded by using RM0.09 at different time points before (baseline) and after injection of carrageenan into the left hindpaw
| RM0.9 P (95% CI) | RM0.5 P (95% CI) | RM 0.09 P (95% CI) | ||
| baseline | ||||
| 1st compared with 1st–3rd average | >0.99 (–11.0 to 11.1) | 0.83 (–13.6 to 8.3) | 0.25 (–1.7 to 8.9) | |
| 1st compared with 1st–5th average | 0.98 (–10.3 to 11.9) | 0.65 (–15.0 to 6.9) | 0.08 (–0.4 to 10.2) | |
| 1st–3rd compared with 1st–5th average | 0.99 (–10.4 to 11.8) | 0.95 (–12.4 to 9.6) | 0.84 (–4.0 to 6.7) | |
| 3 h | ||||
| 1st compared with 1st–3rd average | 0.96 (–9.8 to 12.4) | 0.95 (–9.5 to 12.4) | 0.98 (–4.9 to 5.8) | |
| 1st compared with 1st–5th average | 0.95 (–9.6 to 12.5) | 0.87 (–8.6 to 13.3) | 0.96 (–4.7 to 5.9) | |
| 1st–3rd compared with 1st–5th average | >0.99 (–11.0 to 11.2) | 0.98 (–10.1 to 11.8) | >0.99 (–5.1 to 5.5) | |
| 6 h | ||||
| 1st compared with 1st–3rd average | 0.93 (–9.4 to 12.7) | 0.95 (–9.6 to 12.3) | 0.94 (–4.6 to 6.0) | |
| 1st compared with 1st–5th average | 0.96 (–9.8 to 12.3) | 0.86 (–8.5 to 13.4) | 0.81 (–3.9 to 6.7) | |
| 1st–3rd compared with 1st–5th average | >0.99 (–11.5 to 10.7) | 0.97 (–9.9 to 12.0) | 0.95 (–4.6 to 6.0) | |
| 9 h | ||||
| 1st compared with 1st–3rd average | 0.94 (–9.5 to 12.7) | >0.99 (–11.0 to 10.9) | 0.99 (–5.0 to 5.6) | |
| 1st compared with 1st–5th average | 0.94 (–9.5 to 12.7) | 0.96 (–9.7 to 12.2) | 0.99 (–4.9 to 5.7) | |
| 1st–3rd compared with 1st–5th average | >0.99 (–11.0 to 11.1) | 0.96 (–9.7 to 12.2) | >0.99 (–5.3 to 5.4) | |
| 24 h | ||||
| 1st compared with 1st–3rd average | 0.99 (–10.6 to 11.6) | >0.99 (–11.0 to 10.9) | 0.99 (–5.1 to 5.5) | |
| 1st compared with 1st–5th average | 0.90 (–9.0 to 13.1) | 0.99 (–10.8 to 11.1) | 0.88 | |
| 1st–3rd compared with 1st–5th average | 0.94 (–9.5 to 12.6) | 0.99 (–10.7 to 11.2) | 0.92 |