Table 2.
Risk for Hospital Admission for Patients 18 Years and Older With COVID-19, Mayo Clinic, March Through July 2020
| Characteristic | Total (N=7217) | Hospitalized (N=897) | Unadjusted Model |
Multivariable Model |
|||
|---|---|---|---|---|---|---|---|
| Odds Ratio | 95% CI | Odds Ratio | 95% CI | P | |||
| Age (y), median (range) | 39 (18-99) | 59 (18-99) | — | — | |||
| Age distribution (y), no. (%) | |||||||
| 18-34 | 3054 (42.3%) | 107 | 1 | Reference | 1 | Reference | |
| 35-49 | 1690 (23.4%) | 164 | 2.96 | 2.31-3.81 | 1.87 | 1.40-2.50 | <.001 |
| 50-64 | 1551 (21.5%) | 284 | 6.17 | 4.91-7.81 | 3.05 | 2.30-4.04 | <.001 |
| 65-74 | 524 (7.3%) | 157 | 11.78 | 9.02-15.44 | 5.26 | 3.74-7.39 | <.001 |
| ≥75 | 398 (5.5%) | 185 | 23.92 | 18.2-31.60 | 8.31 | 5.69-12.1 | <.001 |
| Sex, no. (%) | |||||||
| Female | 3533 (49.0%) | 406 | 1 | Reference | 1 | Reference | |
| Male | 3667 (50.8%) | 491 | 1.19 | 1.03-1.37 | 1.15 | 0.96-1.38 | .14 |
| Missing | 17 (0.2%) | 0 | |||||
| Month of COVID-19 diagnosis, no. (%) | |||||||
| March | 126 (1.7%) | 49 | 1 | Reference | 1 | Reference | |
| April | 189 (2.6%) | 79 | 1.13 | 0.71-1.79 | 0.99 | 0.54-1.81 | .98 |
| May | 614 (8.5%) | 118 | 0.37 | 0.25-0.57 | 0.32 | 0.19-0.56 | <.001 |
| June | 3059 (42.4%) | 301 | 0.17 | 0.12- 0.25 | 0.16 | 0.10-0.26 | <.001 |
| July | 3229 (44.7%) | 350 | 0.19 | 0.13- 0.28 | 0.15 | 0.09-0.24 | <.001 |
| Race/ethnicity, no. (%) | |||||||
| Hispanic (all races) | 1141 (15.8%) | 169 | 1.31 | 1.08-1.58 | 2.14 | 1.66-2.75 | <.001 |
| White, non-Hispanic | 4097 (56.8%) | 481 | 1 | Reference | 1 | Reference | |
| Black, non-Hispanic | 668 (9.3%) | 90 | 1.17 | 0.91-1.48 | 1.89 | 1.39-2.57 | <.001 |
| Asian, non-Hispanic | 302 (4.2%) | 50 | 1.49 | 1.07-2.03 | 2.56 | 1.70-3.86 | <.001 |
| All other/missing | 1009 (14.0%) | 107 | 0.89 | 0.71-1.11 | 2.85 | 2.07-3.93 | <.001 |
| CCI score, median (range) | 0 (0-19) | 3 (0-19) | — | — | — | — | — |
| CCI score, no. (%) | |||||||
| 0 | 4291 (59.5%) | 164 | 1 | Reference | — | — | — |
| 1 | 902 (12.5%) | 117 | 3.75 | 2.92-4.81 | — | — | — |
| ≥2 | 2024 (28.0%) | 616 | 11.01 | 9.20-13.25 | — | — | — |
| CCI diabetes mellitus, no. (%) | |||||||
| No | 6541 (90.6%) | 597 | 1 | Reference | 1 | Reference | |
| Yes | 676 (9.4%) | 300 | 7.94 | 6.68-9.45 | 2.50 | 1.99-3.13 | <.001 |
| CCI cardiovascular disease, no. (%) | |||||||
| No | 6916 (95.8%) | 760 | 1 | Reference | 1 | Reference | |
| Yes | 301 (4.2%) | 137 | 6.77 | 5.32-8.59 | 1.56 | 1.13-2.14 | .007 |
| CCI congestive heart failure, no. (%) | |||||||
| No | 6874 (95.2%) | 739 | 1 | Reference | 1 | Reference | |
| Yes | 343 (4.8%) | 158 | 7.09 | 5.65-8.88 | 1.14 | 0.83-1.57 | .42 |
| CCI peripheral vascular disease, no. (%) | |||||||
| No | 6771 (93.8%) | 668 | 1 | Reference | 1 | Reference | |
| Yes | 446 (6.2%) | 229 | 9.64 | 7.88-11.81 | 2.29 | 1.73-3.02 | <.001 |
| CCI chronic obstructive pulmonary disease, no. (%) | |||||||
| No | 6369 (88.2%) | 668 | 1 | Reference | 1 | Reference | |
| Yes | 848 (11.8%) | 229 | 3.16 | 2.66-3.74 | 1.46 | 1.16-1.84 | .001 |
| CCI malignancy, no. (%) | |||||||
| No | 6781 (94.0%) | 763 | 1 | Reference | 1 | Reference | |
| Yes | 436 (6.0%) | 134 | 3.50 | 2.81-4.34 | 1.30 | 0.98-1.71 | .07 |
| CCI liver, no. (%) | |||||||
| No | 6798 (94.2%) | 747 | 1 | Reference | 1 | Reference | |
| Yes | 419 (5.8%) | 150 | 4.52 | 3.64-5.59 | 1.68 | 1.28-2.20 | <.001 |
| CCI renal, no. (%) | |||||||
| No | 6748 (93.5%) | 679 | 1 | Reference | 1 | Reference | |
| Yes | 469 (6.5%) | 218 | 7.76 | 6.37-9.46 | 1.55 | 1.17-2.05 | .002 |
| Body mass index (kg/m2), no. (%) | |||||||
| <18.5 | 156 (2.2%) | 10 | 0.55 | 0.27-1.02 | 0.83 | 0.37-1.87 | .65 |
| 18.5-24.9 | 1444 (20.0%) | 159 | 1 | Reference | 1 | Reference | |
| 25.0-29.9 | 1441 (20.0%) | 238 | 1.60 | 1.29-1.99 | 1.21 | 0.92-1.58 | .17 |
| 30.0-39.9 | 1452 (20.1%) | 324 | 2.32 | 1.89-2.86 | 1.45 | 1.11-1.89 | .006 |
| ≥40 | 505 (7.0%) | 132 | 2.86 | 2.21-3.70 | 1.91 | 1.38-2.64 | <.001 |
| Missing | 2219 (30.7%) | 34 | 0.13 | 0.09-0.18 | 0.14 | 0.09-0.22 | <.001 |
| Smoking, no. (%) | |||||||
| Never | 3716 (51.5%) | 545 | 1 | Reference | 1 | Reference | |
| Former | 944 (13.1%) | 240 | 1.98 | 1.67-2.35 | 1.01 | 0.81-1.26 | .94 |
| Current | 645 (8.9%) | 84 | 0.87 | 0.68-1.11 | 1.14 | 0.84-1.55 | .38 |
| Missing | 1912 (26.5%) | 28 | 0.09 | 0.06-0.12 | 0.09 | 0.05-0.15 | <.001 |
CCI, Charlson Comorbidity Index; COVID-19, coronavirus disease 2019.