Table 2.
Patient | 1 | 2 | 3 | 4 |
---|---|---|---|---|
EDSS | 4.0 | 3.5 | 4.5 | 4.5 |
Lymphocyte count [103/μl] (N: 1−3.3) | 0.82 | 1.47 | 2.25 | 2.82 |
Neutrophil count [103/μl] (N: 1.6−6) | 4.58 | 4.18 | 6.39 | 3.08 |
WBC [103/μl] (N: 4−10.5) | 6.33 | 6.22 | 10.08 | 5.42 |
Monocyte count [103/μl] (N: 0.15−0.6) | 0.55 | 0.46 | 0.7 | 0.33 |
Eosinophil count [103/μl] (N: 0.2−0.5) | 0.26 | 0.08 | 0.1 | 0.24 |
Basophil count [103/μl] (N: 0.01−0.1) | 0.01 | 0.01 | 0.01 | 0.02 |
HCT [%] (N: 37−47) | 38.9 | 37.6 | 37.1 | 40.7 |
RBC [103/μl] (N: 4.2−5.4) | 4.42 | 4.46 | 4.39 | 4.54 |
Hb [g/dL] (N: 12.5−16] | 13.2 | 12.5 | 12.4 | 14.3 |
MCV [fL] (N: 78−100) | 88 | 84.3 | 84.5 | 89.6 |
MCH [pg] (N: 27−31) | 29.9 | 28 | 28.2 | 31.5 |
MCHC [g/dL] (N: 32−36) | 33.9 | 33.2 | 33.4 | 35.1 |
RDW-CV [%] (N: 11.5−14.5) | 13 | 12.9 | 13.3 | 12.3 |
RDW-SD [fL] | 42.1 | 39 | 41.1 | – |
PLT [103/μl] (N: 150−450) | 244 | 250 | 356 | 229 |
MPV [fL] (N: 6−9.5) | 10.4 | 11.3 | 10 | 10.6 |
PDW [fL] (N: 9.8−16.2) | 11.6 | 13.5 | 10.8 | – |
P-LCR [%] (N: 19.1−47) | 27 | 35.6 | 24.3 | 29.2 |
PCT [%] (N: 0.15−0.5) | 0.25 | 0.28 | 0.35 | – |
CRP [mg/L] (N: 0−5) | 1.38 | – | 9.01 | – |
IG [103/μl] (N: 0−0.015) | 0.01 | 0.02 | 0.03 | – |
NRBC [103/μl] (N: 0−0.03) | 0 | 0 | 0 | – |
MICROR [%] (N: 0.14−5.79) | 1.7 | 3.4 | 2.9 | – |
MACROR [%] (N: 3.3–5.56) | 3.5 | 3.9 | 3.9 | – |
ALT [U/L] (N: 0−41) | 14.8 | 24.1 | 15 | 19 |
AST [U/l] (N: 0−40) | 18.4 | 21.5 | 13.9 | 16 |
Total bilirubin [μmol/L] (N: 5−21) | – | – | <2.5 | 8.9 |
Direct bilirubin [μmol/L] (N: 0−3.4) | 4.7 | 3.2 | – | – |
Creatine kinase [U/L] (N: 10−200) | 74 | – | 77 | – |
Serum creatinine [μmol/L] (N: 44−80) | 53 | 50 | 55 | 66 |
GFR [ml/min/1.73 m2] | 125.73 | – | – | 80 |
Blood sodium [mmol/L] (N: 136−146) | – | – | – | 139 |
Blood potassium [mmol/L] (N: 3.5−5) | – | – | – | 4.3 |
TSH [μIU/mL] (N: 0.27−4.2) | – | 2.54 | 0.839 | 1.160 |
General urine test (only abnormal results) |
No abnormal results | – | – | pH = 5; 6−8 leukocytes per high-power field; 2−4 erythrocytes per high-power field |
Head MRI with contrast | Number and size of demyelination lesions with an image similar to the previous examination, without activity signs | Number and size of demyelination lesions with an image similar to the previous examination, without activity signs | Number and size of demyelination lesions with an image similar to the previous examination, without activity signs | Number and size of demyelination lesions with an image similar to the previous examination, without activity signs |
VEP | Abnormal | Abnormal | Abnormal | Abnormal |
BAEP | Normal | Normal | normal | Normal |
NCS | Normal | Normal | Normal | normal |
EEG | Record with focal lesions bilaterally in the parasagittal region | Normal record | Normal record | Record with focal lesions in the left frontotemporal region |
CDD of extracranial vessels | Normal | Normal | Normal | Normal |
Psychological test | Increased anxiety rate | Increased anxiety rate | Normal emotional state | Increased anxiety rate |
EDSS – Expanded Disability Status Scale; N – normal result; ; WBC – white blood cells count; HCT – haematocrit; RBC – red blood cells count; Hb – haemoglobin; MCV – mean corpuscular volume; MCH – mean corpuscular haemoglobin; MCHC – mean corpuscular haemoglobin concentration; PLT – platelets count; MPV – mean platelet volume; PDW – platelet distribution width; P-LCR – platelet large cell ratio; PCT – procalcitonin; CRP – C-reactive protein; IG – immature granulocyte count; NRBC – nucleated red blood cells; MICROR – microcytes (micro red blood cells); MACROR – macrocytes (macro red blood cells); ALT – alanine transaminase; AST – aspartate transaminase; LDH - Lactate dehydrogenase; TSH – thyroid-stimulating hormone; MRI – magnetic resonance imaging; VEP – visual evoked potential; BAEP – brainstem auditory evoked potential; NCS – nerve conduction study; EEG – electroencephalography; CDD – Color-Coded Duplex Doppler. Deviations from the normal results are bold.