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. 2021 Jan 9;104:572–579. doi: 10.1016/j.ijid.2020.12.086

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Tandem clustering analysis for COVID-19 related symptoms. Panel A shows the symptoms’ dispersion plot through main component analysis (MCA); the red color indicates the gastrointestinal cluster, gold shows the respiratory cluster, and blue shows the common cluster (no symptoms stand out). Dimension 1 (Dim 1) and Dimension 2 (Dim 2) shows the variance explained by each one (22.2 and 9.4%, respectively). Panel B shows the frequency and distribution of COVID-19 related symptoms in each cluster identified. Symptoms are indicated as 1 = Conjunctivitis, 2 = Abdominal pain, 3 = Headache, 4 = Sore throat, 5 = Myalgia/Arthralgia, 6 = Breath difficulty, 7 = Diarrhea, 8 = Chills, 9 = Fever, 10 = Runny nose, 11 = Constant dry cough, and 12 = Vomiting).