Table 2.
Assay | Euroimmun IgG | Abbott IgG | Wantai Ab | DiaPro IgG confirmation |
||||
---|---|---|---|---|---|---|---|---|
Platform | ELISA | CLIA (Alinity-i) | ELISA | ELISA |
||||
Antigen | S1 | N | S (RBD) | S1 | S2 | N | ≥2 Ag | |
Sensitivity | ||||||||
≥7−13 dps | n/N | 4/13 | 6/13 | 11/13 | 7/13 | 2/13 | 13/13 | 8/13 |
% | 30.8 | 46.2 | 84.6 | 53.8 | 15.4 | 100 | 61.5 | |
95 % CI | 9.1−61.4 | 19.2−74.9 | 54.6−98.1 | 25.1−80.8 | 1.9−4.5 | 75.3−100.0 | 31.6−86.1 | |
≥14 dps | n/N | 43/45 | 43/45 | 44/45 | 42/45 | 28/45 | 44/45 | 43/45 |
% | 95.6 | 95.6 | 97.8 | 93.3 | 62.2 | 97.8 | 95.6 | |
95 % CI | 84.9−99.5 | 84.9−99.5 | 88.2−99.9 | 81.7−98.6 | 46.5−76.2 | 88.2−99.9 | 84.9−99.5 | |
Specificity | n/N | 82/89 | 88/89 | 89/89 | 85/89 | 89/89 | 75/89 | 88/89 |
% | 92.1 | 98.9 | 100.0 | 95.5 | 100.0 | 84.3 | 98.9 | |
95 % CI | 84.5−96.8 | 93.9−100.0 | 95.9−100.0 | 88.9−98.8 | 95.9−100.0 | 75.0−91.1 | 93.9−100.0 |
dps: days post-onset of symptoms.