Table 2.
Ranking procedure done on the basis of Geometric Mean of Binding and Antigenic Scores of T-cell and B-cell epitopes from each CCnR.
| Consensus Conserved Region (CCnR) | Protein | Coded | MHC-I restricted T-cell |
MHC-II restricted T-cell |
B-cell Epitopes |
Final | |||
|---|---|---|---|---|---|---|---|---|---|
| Sequence | Protein | Immunogenic Score | Antigenic score | Immunogenic score | Antigenic Score | Immunogenic Score | Antigenic Score | Score | |
| 10463-CACAGAAAACTTGTTACTTTATATTGACATTAATGGCAATCTTCATCCAGATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGAGGGTGTTTTAACTGCTGTGGTTATACCTACTAAAAAGGCTGGTGGCACTACTGAAATGCTAGCGAAAGCTTT-10539 | TENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKA | NSP3 | 0.8640 | 0.7361 | 0.9804 | 0.6382 | 0.8810 | 1 | 0.84 |
| 9104-TTAAGGGTTCATTCCTTAATGGTTCATGTGGTAGTGTTGGTTTTAACATAGATTATGACTGTGTCTCTTTTTGTTAC-9211 | KGSFLNGSCGSVGFNIDYDCVSFCY | 3CL-Proteinase | 0.6552 | 0.9049 | 0.9114 | 0.7499 | 0.7143 | 0.7401 | 0.77 |
| 21661-TTTTGTGACTTAAAAGGTAAGTATGTACAAATACCTACAACTTGTGCTAATGACCCTGTGGGTTTTACACTTAAAAACACAGTCTGTACCGTCTGCGGTAT-21728 | FCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCG | NSP10 | 0.9136 | 0.7542 | 0.9818 | 0.3852 | 0.9048 | 0.6813 | 0.74 |
| 5220-TAACACTCCAACAAATAGAGTTGAAGTTTAATCCACCTGCTCTACAAGATGCTTATTACAG-5288 | TLQQIELKFNPPALQDAYY | NSP3 | 0.8106 | 1 | 0.9485 | 0.6714 | 0.3333 | 0.8433 | 0.72 |
| 6706-ATTCTTACCTGGTGTTTATTCTGTTATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTTTTTAGCACATATTCAGTGGATGGTT-6839 | FLPGVYSVIYLYLTFYLTNDVSFLAHIQWMV | NSP4 | 0.9980 | 0.7866 | 0.9933 | 0.3326 | 0.9762 | 0.4726 | 0.70 |