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. 2021 Jan 18;11(1):120. doi: 10.3390/biom11010120

Figure 6.

Figure 6

Different protein-/nucleo-based-prodrug gene-directed enzyme prodrug therapy (GDEPT) systems. (A) Enzymatic hydrolysis of purine prodrugs by PNP and (B) enzymatic hydrolysis of purine and/or pyrimidine prodrugs by LdNDT.