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The level of GDAP1 protein correlates with changes in the pattern of TGN46 modifications. Western blot analysis of total cell extracts from not transfected HeLa cells (far left lane), transfected with empty vector ([-]) or vectors bearing variants of GDAP1 (as indicated). Western blots performed using antibodies against GDAP1 or against the Golgi proteins GM130 and TGN46. The black arrow indicates immature TGN46, the grey arrow shows mature, modified forms.
