TABLE 2.

Studies correlating extent of resection (GTR) with and without DTI

Authors & Year	No. of Pts	DTI Method	% w/ DTI	% w/o DTI	Location/Notes
Chen et al., 2007	7 cavernomas, 3 grade II gliomas	Brainlab iPlan 2.5; 6 gradient directions, b = 1000 sec/mm2	60%	NA	Pontine lesions; DTI used in all cases w/ “great value”
Wu et al., 2007	118 w/ DTI, 120 w/o	MRI protocols changed w/in the study; 6 or 25 gradient directions	72%	52%	Gliomas involving pyramidal tract, p = 0.002
D’Andrea et al., 2012	14 glioma, 4 metastases	Brainlab iPlan 2.6; 12 gradient directions, b = 1000 sec/mm2	100%	NA	All tumors involved CST; multimodal adjuncts used included intraop MRI after dural opening, neuronavigation, intraoperatively acquired tractography, electrical mapping
Ius et al., 2012	190 total, 117 w/ DTI	Not specified	90%	77%	LGGs involving eloquent areas; DTI cohort included fMRI data