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. 2021 Jan 8;294:198282. doi: 10.1016/j.virusres.2020.198282

Table 1.

COVID-19 conventional therapeutics.

Therapeutics Name Target/rational for use Clinical phase status Findings
Drugs Remdesivir an inhibitor of RNA-dependent RNA polymerase (RdRP) Phase III Ongoing No Result Posted
Dexamethasone Inhibition of Strongyloides hyperinfection syndrome Phase IV Recruiting No Result Posted
Hydroxychloroquine Block viral entry by inhibiting glycosylation of host receptors, proteolytic processing, and endosomal acidification. Phase III Completed No Result Posted
Vaccines mRNA-1273 S protein Phase III Recruiting No Result Posted
AZD-1222 S protein Phase III Recruiting No Result Posted
Ad5- nCoV S protein Phase III Recruiting No Result Posted
Antibodies LY-CoV555 S protein Phase III Recruiting No Result Posted
REGN-COV-2 S protein Phase III Recruiting No Result Posted