TABLE 2.

Binding energy and its constituents calculated through MM-PBSA calculations for the protein-ligand complexes.

Complexes	Binding Energy (kJ/mol)	Van der Waal's Energy (kJ/mol)	Electrostatic Energy (kJ/mol)	Polar Solvation Energy (kJ/mol)	SASA Energy (kJ/mol)
NMDAR-hesperidin	−254.160	−365.438	−127.379	268.324	−29.667
TRK-hesperidin	−162.453	−339.164	−106.594	311.526	−28.221
GABA-hesperidin	−156.108	−274.592	−98.771	241.504	−24.249
Interleukin10-hesperidin	−249.671	−316.658	−98.299	191.066	−25.780