Table 3.

Patient outcomes

				Patients (n=2088)
Coma
	Prevalence (ever comatose in 21 days)			1704 (81·6%)
	Coma duration, days*			10·0 (6·0–15·0)
	Persistently comatose until death or day 21			313 (15·0%)
Delirium†
	Prevalence (ever delirious in 21 days)			1147 (54·9%)
		Delirium duration, days*		3·0 (2·0–6·0)
	Delirium subtype‡§
		Ever hypoactive		388/925 (41·9%)
			Hypoactive only delirium duration, days	2·0 (1·0–4·0)
		Ever hyperactive		479/925 (51·8%)
			Hyperactive only delirium duration, days	2·0 (1·0–4·0)
Acute brain dysfunction (coma or delirium)
	Coma or delirium duration, days			12·0 (7·0–18·0)
	Days alive without delirium or coma in 21 days¶			5·0 (0·0–14·0)
Index length of stay in ICU in 28 day period				14·0 (8·0–25·0)
Ventilator-free days in 28 day period‖				7·0 (0·0–20·0)
Vital status on day 28
	Dead			601 (28·8%)
	Alive			1416 (67·8%)
	Unknown			71 (3·4%)

Data are n (%), median (IQR), or n/N (%). ICU=intensive care unit.

^*If a patient was both delirious and comatose on the same day, that day was counted for both delirium duration and coma duration outcomes since they were examined as separate outcomes.

^†Patients were not screened for coma or delirium after discharge from the ICU and thus during the days after index ICU discharge until the day of death or the end of 21 days (whichever occurred first) patients were considered to be awake without delirium.

^‡Ever hypoactive and ever hyperactive delirium categories during the 21-day study period were not mutually exclusive.

^§Data on delirium subtype not reported for 222 of 1147 patients.

^¶Number of days within the 21-day study period on which patients were alive and free of delirium or coma; this variable was truncated at 21 days because the study design only collected daily assessment data for a maximum of 21 days, ICU discharge or death, whichever happened first.

^‖Number of days patients were alive and did not require mechanical ventilation (invasive or non-invasive) in a 28-day period.