Table 1.
Baseline characteristics of the patients with candidemia, including demographics, comorbid conditions, immunosuppression, and admission characteristics.
| Characteristics | n (%) | |
|---|---|---|
| Demographics and Comorbidities | ||
| Age (years, mean ± SD) | 65.71 | ±17.175 |
| Female | 84 | (49.4) |
| Diabetes mellitus | 50 | (29.4) |
| Hemodialysis | 29 | (17.1) |
| End-stage renal disease | 10 | (5.9) |
| Acute kidney injury | 19 | (11.2) |
| Immunosuppression | ||
| Malignancy | 86 | (50.6) |
| Non-hematologic | 62 | (36.5) |
| Hematologic | 20 | (11.8) |
| Both | 4 | (2.4) |
| Chemotherapy | 38 | (22.4) |
| <1 week from infection | 10 | (5.9) |
| Immunotherapy | 3 | (1.8) |
| Hematopoietic stem cell transplant recipient | 7 | (4.1) |
| Auto-transplant | 3 | (1.8) |
| Allo-transplant | 3 | (1.8) |
| Both | 1 | (0.6) |
| Neutropenia | 21 | (12.4) |
| 1000–1500/mm3 | 3 | (1.8) |
| 500–1000/mm3 | 6 | (3.5) |
| <500/mm3 | 12 | (7.1) |
| Current steroids | 36 | (21.2) |
| Solid organ transplant recipient | 3 | (1.8) |
| Congenital syndromes | 3 | (1.8) |
| Other immunosuppressants | 9 | (5.3) |
| Admission Characteristics | ||
| Unit | ||
| Regular ward | 76 | (44.7) |
| Critical care unit | 82 | (48.2) |
| Emergency department | 12 | (7.1) |
| Abdominal surgery within 30 days | 45 | (26.5) |
| Antibiotics use within 30 days | 161 | (94.7) |
| Antifungals use within 30 days | 45 | (26.5) |
| Fluconazole | 31 | (18.2) |
| Voriconazole | 2 | (1.2) |
| Lipid formulation of amphotericin B | 4 | (2.4) |
| Caspofungin | 8 | (4.7) |
| Anidulafungin | 2 | (1.2) |
| Duration of previous antifungal (days, mean ± SD) | 13.43 | ±15.66 |
| Mechanical ventilation | 83 | (48.8) |
| Parenteral nutrition | 44 | (25.9) |
| Central venous catheter | 117 | (68.8) |
| Source | ||
| Gastrointestinal translocation | 57 | (33.5) |
| CLABSI | 40 | (23.5) |
| Urinary tract infection | 17 | (10) |
| Vertebral abscess | 1 | (0.6) |
| Aortoiliac graft infection | 1 | (0.6) |
| Unknown | 54 | (31.8) |
Data are presented as number (percentage) unless otherwise specified. CLABSI: Central Line-Associated Bloodstream Infection.