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Schematic Protocol of i-QSAR Analysis to Study the Response of Drug Candidates for Humans through Extrapolation of Bats/Pangolins and If Possible, through Cats/Dogs or Common Experimental Mammals.
a is a constant term, X1 and X2 are coefficients of log10(1/IC50[Animal]) and D3 modeled descriptors, respectively, in the interspecies equation.
