Table 6.
Item | No. of studies | Prevalence% | 95% CI | n | I2 | T2 | P-value for testing heterogeneity. | Egger's test P |
---|---|---|---|---|---|---|---|---|
Demographical characteristics | ||||||||
Age (mean in years) | 21 | 46.8 | 41.0–52.6 | 20 | 99.78 | 180.467 | <0.001 | 0.0438 |
Male | 33 | 54.0 | 51.3–56.7 | 32 | 69.535 | 0.040 | <0.001 | 0.0189 |
Co-Morbidities | ||||||||
Co-morbidities | 17 | 29.5 | 19.0–36.6 | 16 | 98.738 | 1.372 | <0.001 | 0.8677 |
DM | 17 | 13.8 | 8.7–21.1 | 17 | 96.645 | 1.076 | <0.001 | 0.0183 |
Hypertension | 15 | 11.7 | 5.7–22.6 | 14 | 98.66 | 2.241 | <0.001 | 0.0025 |
CVD | 16 | 9.7 | 6.5–14.2 | 15 | 92.455 | 9.639 | <0.001 | 0.0441 |
COPD | 14 | 3.9 | 2.9–5.3 | 13 | 62.282 | 0.132 | <0.001 | 0.1004 |
Clinical manifestations | ||||||||
Fever | 31 | 82.0 | 67.7–90.8 | 30 | 98.557 | 4.531 | <0.001 | 0.0117 |
Cough | 29 | 54.3 | 45.5–62.9 | 28 | 93.792 | 0.779 | <0.001 | 0.0090 |
Fatigue | 21 | 30.2 | 23.3–38.1 | 20 | 83.651 | 0.465 | <0.001 | 0.9873 |
Sputum | 13 | 28.5 | 21.2–37.2 | 12 | 83.783 | 0.390 | <0.001 | 0.7643 |
Sore Throat | 10 | 21.7 | 14.6–31.0 | 9 | 74.296 | 0.338 | <0.001 | 0.3871 |
Headache | 13 | 11.0 | 7.9–15.2 | 12 | 68.412 | 0.227 | <0.001 | 0.4517 |
Hemoptysis | 3 | 5.3 | 3.0–8.9 | 2 | 0 | 0 | 0.424 | 0.1580 |
Laboratory findings | ||||||||
Leukocytosis | 16 | 7.5 | 4.5–12 | 15 | 85.716 | 0.842 | <0.001 | 0.0093 |
Leukopenia | 17 | 16.0 | 9.5–25.7 | 16 | 93.670 | 1.342 | <0.001 | 0.2359 |
Lymphopenia | 17 | 41.9 | 30.1–54.7 | 16 | 97.302 | 1.074 | <0.001 | 0.0956 |
High Creatinine | 7 | 7.7 | 3.2–17.3 | 6 | 86.947 | 1.135 | <0.001 | 0.1139 |
High LDH | 10 | 51.5 | 40.3–62.6 | 9 | 94.679 | 0.463 | <0.001 | 0.0074 |
CRP | 12 | 48.1 | 29.8–66.9 | 11 | 96.494 | 1.622 | <0.001 | 0.0215 |
ESR | 4 | 23.5 | 11.1–42.9 | 3 | 79.739 | 0.752 | 0.002 | 0.0214 |
Complications | ||||||||
RNA Anemia | 13 | 98.2 | 96.2–99.2 | 12 | 0 | 0 | 0.974 | 0.0001 |
Hospitalization | 23 | 83.7 | 76.0–89.3 | 22 | 89.67 | 0.784 | <0.001 | 0.0613 |
Bilateral Pneumonia | 19 | 70.9 | 58.2–81.0 | 18 | 92.552 | 1.207 | <0.001 | 0.0485 |
Unilateral Pneumonia | 15 | 26.2 | 14.6–42.2 | 14 | 91.829 | 1.723 | <0.001 | 0.2087 |
ARDS | 6 | 23.6 | 12.9–39.2 | 5 | 91.623 | 0.703 | <0.001 | 0.7139 |
Shock | 7 | 8.5 | 4.4–10.8 | 6 | 74.476 | 0.516 | <0.001 | 0.0254 |
Discharge | 16 | 43.5 | 24.9–64.2 | 15 | 98.13 | 2.84 | <0.001 | 0.8226 |
Death | 17 | 10.5 | 6.8–16.1 | 16 | 94.32 | 0.816 | <0.001 | 0.0214 |
No, number; CI, confidence interval; DM, diabetes mellitus; CVD, cardiovascular disease; COPD, chronic obstructive pulmonary disease ICU, intensive care unit. LDH, lactate dehydrogenase; ARDS, acute respiratory distress syndrome; CRP, C-reactive protein.
Q Cochran's Q statistic for heterogeneity. n, degree of freedom, I2 Index for the degree of heterogeneity. T2 Tau-squared measure of heterogeneity.