Table 3.
Outcomes of patients according to the use of metformin before propensity score analysis.
| Metformin use |
||||
|---|---|---|---|---|
| All (N = 2449) | No (N = 953) | Yes (N = 1496) | P value | |
| Day 7 | ||||
| Composite endpoint | 695 (28.4%) | 276 (29.0%) | 419 (28.0%) | 0.6134 |
| IMV | 456 (18.6%) | 140 (14.7%) | 316 (21.1%) | 0.0001 |
| Death | 275 (11.2%) | 153 (16.1%) | 122 (8.2%) | <0.0001 |
| Day 28 | ||||
| Composite endpoint | 857 (35.0%) | 369 (38.7%) | 488 (32.6%) | 0.0023 |
| IMV | 477 (19.5%) | 149 (15.6%) | 328 (21.9%) | 0.0001 |
| Death | 512 (20.9%) | 273 (28.6%) | 239 (16.0%) | <0.0001 |
Composite endpoint combines tracheal intubation for mechanical ventilation (IMV) and death.