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. 2021 Jan 25;186(Suppl 1):479–485. doi: 10.1093/milmed/usaa310

FIGURE 2.

FIGURE 2.

Representative muscle tension tracings of triceps surae muscles before and after crush injury with or without systemic 4-aminopyridine (4-AP) (150 μg/kg, ip) (A) and local 4-AP thermogel (C) treatments. Figures (B) and (D) show the muscle tension as % increase over crush after systemic and local 4-AP treatments, respectively. Bar graphs showing area under the curve (E, G) and peak muscle tension (F, H) before and after systemic or local 4-AP treatment, respectively. Figures E and F are for systemic, and figures G and H are for local 4-AP treatments. Data are represented as mean ± SEM. n = 6/group for systemic 4-AP, n = 3/group for local 4-AP. *P < 0.05, **P < 0.01, ***P < 0.001 by one-way ANOVA followed by Tukey’s multiple comparisons post hoc test.