TABLE 2.
Laboratory findings of recovery and death patients with severe or critical COVID-19.
| Characteristics | Normal range | Recovery (n = 60) | Death (n = 14) | P Value |
|---|---|---|---|---|
| Blood routine | ||||
| White blood cell count, × 109/L | 3.5-9.5 | 6.3 (4.2-8.4) | 7.3 (3.7-11.3) | 0.815 |
| Lymphocyte count, × 109/L | 1.1-3.2 | 0.6 (0.5-1.0) | 0.6 (0.5-0.8) | 0.320 |
| Neutrophil count, × 109/L | 1.8-6.3 | 5.0 (2.9-7.1) | 6.3 (2.8-10.0) | 0.508 |
| Lymphocyte ratio, 100% | 0.2-0.5 | 0.1 (0.06-0.2) | 0.1 (0.05-0.16) | 0.258 |
| Neutrophil ratio, 100% | 0.4-0.75 | 0.8 (0.7-0.9) | 0.9 (0.8-0.9) | 0.495 |
| Monocyte ratio, 100% | 0.03-0.1 | 0.01 (0.03-0.06) | 0.01 (0.04-0.08) | 0.304 |
| Blood biochemistry | ||||
| Alanine aminotransferase, U/L | 9-40 | 31(18.5-47) | 34.5 (19-59) | 0.793 |
| Aspartate aminotransferase, U/L | 15-45 | 33 (20-45) | 37 (22-49) | 0.399 |
| Lactate dehydrogenase, U/L | 125-243 | 320.5 (255-409.5) | 485.5 (338-659) | 0.003 |
| Creatinine, μmol/L | 41-73 | 65.5 (55.5-82) | 78 (66-94) | 0.077 |
| Total cholesterol, mmol/L | 2.85-5.69 | 3.91 (3.36-4.26) | 3.86 (3.30-4.60) | 0.978 |
| Triacylglycerol, mmol/L | 0.45-1.69 | 1.37 (1.12-1.67) | 1.44 (1.15-1.96) | 0.783 |
| Creatine kinase, U/L | <171 | 73.3 (39.3-132.2) | 115 (62.4-179.8) | 0.031 |
| Creatine kinase-MB, U/L | <0.6 | 1.4 (1.0-2.4) | 1.4 (1.2-4.0) | 0.170 |
| Troponin I, μg/L | <0.2 | 0.03 (0.03-0.03) | 0.03 (0.03-0.1) | 0.418 |
| Myoglobin, ng/mL | 12-75 | 31.4 (17-48.4) | 71.6 (37.6-109.2) | 0.005 |
| Brain natriuretic peptide, pg/mL | <100 | 252 (57-1024) | 671 (373-1519) | 0.041 |
| Coagulation function | ||||
| Activated partial thromboplastin time, s | 22-36 | 34.5 (31.3-39.6) | 38.1 (32.8-41.5) | 0.217 |
| Prothrombin time, s | 10-13 | 13.2 (12.5-14.3) | 13.8 (12.3-15.7) | 0.412 |
| International normalized ratio | 0.8-1.25 | 1.1 (1.0-1.1) | 1.2 (1.0-1.2) | 0.285 |
| Fibrinogen, g/L | 2-4 | 4.8 (4.0-5.5) | 4.3 (4.1-5.4) | 0.995 |
| Thrombin time, s | 14-21 | 15.6 (15.0-16.5) | 15.1 (14.7-16.1) | 0.115 |
| D-dimer, mg/L | <0.05 | 0.46 (0.3-1.3) | 0.84 (0.5-5.1) | 0.033 |
| Infection-related biomarkers | ||||
| C-reaction protein, mg/L | <10.0 | 47.1 (28.6-88.8) | 60.4 (28.2-99.8) | 0.777 |
| Procalcitonin, ng/mL | <0.05 | 0.04 (0.04-0.07) | 0.07 (0.04-0.27) | 0.174 |
| Chest CT findings | ||||
| Bilateral distribution of patchy shadows or ground glass opacity | NA | 60 (100%) | 14 (100%) | 1.000 |
Abbreviations: NA, not available. Data are reported as n (%) or median (IQR). The P value represents the difference between COVID-19 recovery and death patients. P value <0.05 was considered significant difference (Bold font).