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. 2020 Oct 26;5(1):46–59. doi: 10.1002/ags3.12406

Table 3.

Patient mortality in all cases (N = 395)

Clinicopathological factors Total No. EGJ‐cancer‐specific survival Relapse‐free survival Overall survival
No. of events Univariate HR (95% CI) Multivariate HR (95% CI) No. of events Univariate HR (95% CI) Multivariate HR (95% CI) No. of events Univariate HR (95% CI) Multivariate HR (95% CI)
Siewert classification
Type I (vs Type II) 59 20

1.02 (0.61‐1.62)

P = .94

1.81 (1.06‐2.97)

P = .031

28

0.96 (0.62‐1.41)

P = .83

1.35 (0.87‐2.03)

P = .18

27

0.93 (0.60‐1.38)

P = .72

1.43 (0.91‐2.18)

P = .12

Type III (vs Type II) 56 27

1.83 (1.17‐2.78)

P = .0094

0.93 (0.59‐1.44)

P = .76

37

1.69 (1.16‐2.41)

P = .0071

0.95 (0.64‐1.38)

P = .81

35

1.61 (1.09‐2.31)

P = .018

0.92 (0.61‐1.33)

P = .65

The multivariate, Cox proportional hazard regression model initially included gender, age, year of surgery, body mass index, tumor diameter, tumor location by Siewert classification, existence of Barrett's esophagus, disease stage, tumor differentiation, lymphatic invasion, venous invasion, surgical approach, operative time, blood loss volume, blood transfusion, resection margin, preoperative complication, adjuvant chemotherapy.

A backward elimination with a threshold of P = .20 was used to select variables in the final model.

Abbreviations: CI, confidence interval; HR, hazard ratio.