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. 2021 Jan 25;16(1):e0245831. doi: 10.1371/journal.pone.0245831

Fig 4. Histology of WT and Pah KO livers in mouse and pig.

Fig 4

Standard H&E and Masson’s trichrome sections show no appreciable difference between WT and Pahenu2/enu2 mice or WT and PAHR408W/R408W pigs. Similarly, immunohistochemistry showed similar levels and ubiquitous distribution of expression of the wild type and mutant protein in both models/species.