Table 3.
Plasma Cytokine Concentrations Covid-19 vs Controls.
| Cytokine | Control, mean (SD) | Covid19 ICU Day 1, mean (SD) |
|---|---|---|
| IL-1b | 2.87 (1.70) | 8.82 (9.11)* |
| IL-1ra | 117.07 (73.68) | 1139.83 (766.61)* |
| IL-2 | 3.63 (2.45) | 7.90 (2.60)* |
| IL-4 | 1.51 (0.47) | 3.44 (1.06)* |
| IL-6 | 4.19 (4.30) | 59.93 (71.04)* |
| IL-7 | 14.83 (8.31) | 32.23 (6.09)* |
| IL-8 | 5.02 (2.79) | 22.15 (13.84)* |
| IL-9 | 223.28 (74.14) | 284.05 (29.02) |
| IL-10 | 0.74 (1.03) | 8.55 (6.83)* |
| IL-12 | 3.39 (1.72) | 4.75 (2.18) |
| IL-13 | 2.49 (1.26) | 6.90 (6.52)* |
| IL-17A | 12.60 (6.76) | 24.50 (3.99)* |
| Eotaxin | 37.46 (15.72) | 42.17 (19.43) |
| FGF basic | 37.76 (17.71) | 53.92 (5.92) |
| G-CSF | 32.94 (15.61) | 82.80 (49.80)* |
| GM-CSF | 0.96 (0.61) | 2.19 (2.64) |
| IFN-g | 4.53 (3.08) | 26.67 (18.56)* |
| IP-10 | 397.88 (167.56) | 3856.66 (2801.47)* |
| MCP-1 | 22.52 (3.73) | 178.12 (220.31)* |
| MIP-1a | 1.31 (1.50) | 6.28 (8.51) |
| PDGF-bb | 472.64 (614.86) | 753.39 (448.80) |
| MIP-1b | 191.84 (60.92) | 243.33 (24.72) |
| RANTES | 3431.39 (1982.90) | 4025.62 (1694.89) |
| TNF-a | 88.45 (29.10) | 158.57 (77.31)* |
*
Denotes significant difference vs control (Bonferroni corrected).