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. 2020 Dec 14;138:155389. doi: 10.1016/j.cyto.2020.155389

Table 4.

Correlations between Cytokine Concentration and Outcome.

Cytokine 30-day Mortality C-reactive protein SAPS3 SOFA ICU day 1 Lowest PaO2/FiO2 ICU day 1 Acute Kidney Injury
IL-1b 0.212 0.344 −0.031 0.144 −0.625 * 0.659 *
IL-1ra 0.297 0.711* 0.278 0.195 −0.722 * 0.715 *
IL-2 0.335 0.388* 0.338 −0.003 −0.413* 0.421*
IL-4 0.351* 0.459* 0.270 0.192 −0.697 * 0.667 *
IL-6 0.410* 0.785* 0.208 0.290 −0.722* 0.760 *
IL-7 0.258 0.250 −0.044 −0.058 −0.567 * 0.559 *
IL-8 0.503* 0.715* 0.239 0.344 −0.681 * 0.728*
IL-9 0.311 0.420* 0.017 −0.030 −0.450* 0.405 *
IL-10 0.463* 0.484* 0.346 0.223 −0.667* 0.614 *
IL-12 0.334 0.106 −0.165 −0.143 −0.217 0.122
IL-13 0.152 0.373* 0.010 0.269 −0.532 * 0.637 *
IL-17a 0.286 0.518* 0.086 −0.021 −0.656* 0.705 *
Eotaxin 0.149 −0.124 0.211 0.266 −0.105 0.101
FGF basic 0.416* 0.245 0.239 −0.031 −0.554 * 0.520 *
G-CSF 0.334 0.431* 0.496 * 0.437* −0.586 * 0.592 *
GM-CSF 0.287 0.201 −0.130 0.134 −0.318 0.353
IFN-g 0.308 0.704* 0.310 0.368 −0.621* 0.692 *
IP-10 0.410* 0.695* 0.361 0.357 −0.704* 0.826 *
MCP-1 0.439* 0.619* 0.280 0.476* −0.635* 0.762 *
MIP-1a 0.281 0.422* 0.504* 0.460* −0.114 0.274
PDGF-bb 0.132 0.348 0.282 −0.163 −0.426 * 0.381 *
MIP-1b 0.301 0.418* 0.113 0.072 −0.338 0.304
RANTES 0.226 0.177 0.078 0.25 −0.186 0.219
TNF-a 0.410* 0.590* 0.546* 0.432* −0.568* 0.577 *
*

Denotes significant correlation (p < 0.05).