Table 3.
Fungal metabolites against viral pathogens.
| Name of the compound | Organisms | Active against | References |
|---|---|---|---|
| Aphidicolin | Cephalosporium aphidicola | HSV 1 and 2 | Hanson (1972) |
| Hyalodendrin A | Penicillium turbatu | Polio, Coxsackie viruses | Becher (1976) |
| Stachybogrisephenone B, Grisephenone A, and 3,6,8-Trihydroxy-1-methylxanthone | Stachybotrys sp. | Enterovirus-71 | Qin et al. (2014) |
| Halovirs A–E and Simplicilliumtide J | Scytalidium sp. | HSV | Rowley et al. (2003); Youssef et al. (2019) |
| 11a-dehydroxyisoterreulactone A, Arisugacin A, Isobutyrolactone II, and Aspernolide A | Aspergillus terreus SCSGAF0162 | HSV | Nong et al. (2014) |
| Balticolid | Ascomycetous strain 222 | HSV | Shushni et al. (2011) |
| Equisetin | Fusarium heterosporum | HIV | Shushni et al. (2011) |
| Phomasetin | Phoma sp. | HIV | Singh et al. (1999) |
| Integric acid | Xylaria sp. | HIV | Rowley et al. (2004) |
| Stachyflin | Stachybotrys sp. RF-7260 | Influenza virus | Minagawa et al. (2002) |
| Oxoglyantrypine, Norquinadoline A, Deoxynortryptoquivaline, Deoxytryptoquivaline, Tryptoquivaline, and Quinadoline B | Cladosporium sp. | Influenza virus | Peng et al. (2013) |
| Cladosin C | Cladosporium sphaerospermum 2005-01-E3 | Influenza virus | Wu et al. (2014) |
| (Z)-5-(Hydroxymenthyl)-2-(6′)-methylhept-2′-en-2′-yl)-phenol, Diorcinol, and IFV Cordyol C | A. sydowii ZSDS1-F6 | Influenza virus | Wang et al. (2014) |
| Rubrolide S | A. terreus OUCMDZ-1925 | Influenza virus | Zhu et al. (2013) |
| Asperterrestide A | A. terreus SCSGAF0162 | Influenza virus | He et al. (2013) |
| Isoaspulvinone E, Aspulvinone E, and Pulvic acid | A. terreus Gwq-48 | Influenza virus | Gao et al. (2013) |
| Emerimidine A and Emerimidine B | Emericella sp. (HK-ZJ) | Influenza virus | Zhang et al. (2011) |
| Purpurquinone B, Purpurquinone C, Purpuresters A, and TAN-931 | P. purpurogenum JS03-21 | Influenza virus | Wang et al. (2011) |
| Sorbicatechol A and Sorbicatechol B | P. chrysogenum PJX-17 | Influenza virus | Peng et al. (2014) |
| Tetrahydroaltersolanol C and Alterporriol Q | Alternaria sp. ZJ-2008003 | Porcine reproductive and respiratory syndrome | Zheng et al. (2012) |
| Sansalvamide A (43) | Fusarium sp. | Molluscum contagiosum virus | Hwang et al. (1999) |
| 22-O-(N-Me-L-valyl)-21-epiaflaquinolone | Aspergillus sp. XS-20090B15 | Respiratory syncytial virus | Prieto and Castro (2005) |
| B (44) | |||
| Extracts | Agaricus subrufescens | HSV-1 | Bruggemann et al. (2006) |
| GFAHP | Grifola frondosa | HSV | Gu et al. (2007) |
| Beta-glucan-protein | Agaricus subrufescens | HSV | Yamamoto et al. (2013) |
| Aurenitol | Chaetomium coarctatum | Influenza A (H3N2) | Sacramento et al. (2015) |
| Extracts | Lentinula edodes | HPV | Rincão et al. (2012) |
| Polysaccharopeptide | Trametes versicolor | HIV | Collins and Ng (1997) |
| Polysaccharides | Agaricus subrufescens | HPV | Faccin et al. (2007) |
| Extracts | Trametes versicolor | Influenza, HSV | Krupodorova et al. (2014) |
| Adenosine | Cordyceps militaris | HIV protease | Jiang et al. (2011) |
| Velutin | Flammulina velutipes | HIV-reverse transcriptase | Wang and Ng (2001) |
| 4.5 kDa protein | Russula paludosa | HIV protease | Wang et al. (2007) |
| Ganoderic acid | Ganoderma lucidum | HIV protease and HBV | Min et al. (1998) |
| Brefeldin A | Penicillium sp. FKI-7127 | Dengue viruses, ZIKV, and Japanese encephalitis virus | Raekiansyah et al. (2017) |
| Ganodermadiol, applanoxidic acid G triterpenoids, and lucidadiol | Ganoderma pfeifferi Bres. | Influenza virus type A and HSV-1 | Mothana et al. (2003) |
| Cordycepin (also named 3′-deoxyadenosine) | Cordyceps militaris | Influenza viral, HIV-1 RT, Epstein-Barr virus, andRota virus | Yong et al. (2018) |
| Ganodermic acids are A, AM1, B, β, C1, C2,C6, D, Df, DM, E, F, G, H,J,K, Mc, Me, Nf, Mk, N, P, R, S, Sz,T, TR,TQ, X, and Y | Ganoderma lucidum | HIV-1 and HBV | Hsu and Yen (2014) |
| Hispidin and hispolon | Inonotus hispidus (Bull.) P. Karst. | Influenza virus type A and type B | Li and Wang (2006) |
| PSK Krestin and PSP | Trametes versicolor | HIV-1 | Mlinaric et al. (2005) |
| Velutin and Flammulin proteins | Flammulina velutipes | HIV-1 reverse transcriptase | Wang and Ng (2001) |
| Trypilepyrazinol, (+)-neocitreoviridin, and 3β-hydroxyergosta-8,14,24 (28)-trien-7-one | Penicillium sp. | HIV-1, HCV, and Influenza | Li et al. (2019) |
| Physcion, Neoechinulin D, and Dihydroauroglaucin | Eurotium chevalieri | Influenza A virus | Bovio et al. (2019) |
| Isobutyrolactone II | Aspergillus sp. | HSV-1 | Liu et al. (2020) |