Table 6.
Actinobacterial metabolites against viral pathogens.
| Name of the compound | Organism | Active against | References |
|---|---|---|---|
| 9-Methyl strptimidone | Streptomyces sp. S-885 | Poliovirus | Swallow et al. (1975) |
| Rifampin | Streptomyces mediterranei | Vaccinia and pox viruses | De Clercq (1973) |
| Novobiocin | Streptomyces spheroids (Actinomycetales) | Antiviral activity | Murray et al. (1982) |
| Guanine-7-N-oxide | Streptomyces sp. | Rhabdovirus and infectious pancreatic necrovirus | Nakagawa et al. (1985) |
| Antimycin A1a | Streptomyces kaviengensis | Western equine encephalitis virus | Raveh et al. (2013) |
| Xiamycins C-E | Streptomyces sp. #HK18 | Porcine epidemic diarrhea virus, and HIV | Kim et al. 2016; Xu et al. (2014) |
| Pentapeptide 4862F-N,N,N-(trimethylated)-Tyr-L-Leu-L-Val-L-Leu-(dehydrated)-His | Streptomyces albosporus I03A-04862 | HIV-1 | Liu et al. (2012) |
| 4-amino-3-hydroxy-5-(4-methoxyphenyl) pentanoic acid | Streptomyces sp. CPCC 202950 | HIV-1 | Chen et al. (2018) |
| Daptomycin and Nanchangmycin | Streptomyces nanchangensis, Streptomyces roseosporus | ZIKV | Barrows et al. (2016); Pascoalino et al. (2016); Rausch et al. (2017) |
| Chartreusin | Streptomyces chartreusis | Influenza A | Miyakawa et al. (1958) |
| Mannose specific pradimicin-A (PRMA) | Actinomadura hibisca | HIV | Tanabe-Tochikura et al. (1990) |
| Actinohivin | Longispora albida gen. nov, sp. nov | HIV | Chiba et al. (2004); Takahashi et al. (2005) |
| Benzastatin C, a 3-chloro-tetrahydroquinolone alkaloid | Streptomyces nitrosporeus | HSV-1, HSV-2, and vesicular stomatitis virus | Lee et al. (2007) |
| JBIR-68 | Streptomyces sp. RI18 | Influenza virus | Takagi et al. (2010) |
| Methylelaiophylin | Streptomyces melanosporofaciens | Newcastle disease virus | Lee et al. (2011) |
| Furan-2-yl acetate (C6H6O3) | Streptomyces VITSDK1 spp. | Fish nodavirus | Suthindhiran et al. (2011) |
| Di-n-octyl phthalate and bis (2-methylheptyl) phthalate | Streptomyces parvus | HCV | Elnaby et al. (2016) |
| Fattiviracin A1 | Streptomyces microflavus | Antiviral activity | Yokomizo et al. (1998) |
| Musacin C | Streptomyces griseovirdis | Antiviral activity | Schneider et al. (1996) |
| MM461156 | Actinomadura pelletieri | Antiviral activity | Ashton et al. (1990) |
| FK 506 | Streptomyces tsukubaensis | Antiviral activity | Reis et al. (2006) |
| Benzastatin C | Streptomyces nitrosporeus | Antiviral activity | Kuzuyama and Seto (2003); Lee et al. (2007) |
| (4S)-4-hydroxy-10-methyl-11-oxo-dodec-2-en-1,4-olide | Streptomyces sp. Smu03 | Influenza A virus | Li et al. (2018) |
| Ahmpatinini Bu | Streptomyces sp. CPCC 202950 | HIV-1 | Teixeira et al. (2014) |
| 4862F | Streptomyces albosporus I03A-04862 | HIV-1 | Teixeira et al. (2014) |
| Narasin | Streptomyces aureofaciens | Dengue virus | Teixeira et al. (2014) |