Table 2.

Diarylureas as antibacterials and antifungals.

Structure	Compd	Activity	Ref
Antibacterial activity
	8	MIC50 = 0.05 µg/mL (S. aureus ATCC 12600 and MRSA)	[55]
	PK150	MIC = 0.3 µM (S. aureus NCTC 8325)	[56]
	Sorafenib (BAY-43-9006)	MIC = 3 µM (S. aureus NCTC 8325)	[56]
	Regorafenib (BAY-73-4506)	MIC = 3 µM (S. aureus NCTC 8325)	[56]
	Triclocarban (TCC)	MIC50 = 0.5 µg/mL (S. aureus)	[55]
	6 (Flucofuron)	MIC = 0.25 mg/L (S. aureus NCTC 8325; ATCC 12598 and S. epidermidis ATCC 12228; 35984)	[58]
	9	MIC = 0.5‒8.0 µg/mL (different gram-positive bacteria)	[59]
	10	Inhibition zones = 14.0 mm Gram (+) B. subtilis NCTC-10400 and Gram (‒) P. aeruginosa ATCC 10145 and E. coli ATCC 23282	[61]
	PQ401	MIC = 4 µg/mL (different S. aureus) MBC = 4 g/mL (S. aureus VRS1 strains)	[62]
	11	Inhibition zone = 23 mm, at a concentration of 200 µg/mL (P. mirabilis ATCC 19181)	[63]
	12	Inhibition zone = 24 mm, at a concentration of 200 µg/mL (P. mirabilis ATCC 19181)	[63]
	13	MIC = 31.3 µg/mL (S. boydii ATCC 9905; E. faecalis ATCC 29212; B. cereus ATCC 10987; K. pneumoniae ATCC 10031)	[65]
	14	MIC = 31.3 µg/mL (S. boydii ATCC 9905; E. faecalis ATCC 29212; B. cereus ATCC 10987; K. pneumoniae ATCC 10031)	[65]
	15	MIC = 10 µg/mL (MRSA NRS123)	[67]
	16	MIC = 8 µg/mL (MRSA NRS123)	[67]
	17	MIC = 10 µg/mL (MRSA NRS123)	[67]
	18	MIC = 2‒4 µg/mL (various MRSA)	[67,68]
	19	MIC = 2‒4 µg/mL (various MRSA)	[68]
	20	MIC = 6.25 µg/mL (M. tuberculosis H37Rv)	[69]
	21	MIC = 3.125 µg/mL (M. tuberculosis H37Rv)	[69]
	22	MIC = 6.0 µg/mL (M. tuberculosis pathogenic strain H37Rv) MIC = 2.0 µg/mL (M. tuberculosis nonpathogenic strain mc26030)	[70]
	23	MIC = 5.2 µg/mL (M. tuberculosis pathogenic strain H37Rv) MIC = 1.0 µg/mL (M. tuberculosis nonpathogenic strain mc26030)	[70]
Antifungal activity
	24	Inhibition, at 30 μM, of the growth of P. obscurans by 80% and P. viticola and 100%, after 120 h exposure	[71]