Table 2.
Analysis of synonymous and nonsynonymous pairing of TBEV isolates and tick population on TBEV RNA copy numbers per infected tick separately for Lower Saxony and Bavaria. The p-values were calculated by the Mann-Whitney U test.
| TBEV Area and Focus (Tick Origin) |
Pairing (Virus Isolate) |
All Data | Outliers Removed | ||||
|---|---|---|---|---|---|---|---|
| Median | Minimum; Maximum | p-Value | Median | Minimum; Maximum | p-Value | ||
| Lower Saxony | Nonsynonymous | 842 | 16; 12,400,000 | <0.01 * | 781 | 16; 112,000 | 0.66 |
| Synonymous | 34,200 | 38; 46,100,000 | 915 | 38; 106,000 | |||
| Barsinghausen | Nonsynonymous (P19) | 2360 | 105; 250,000 | <0.01 * | 2195 | 105; 112,000 | 0.49 |
| Synonymous(P51) | 67,950 | 58; 46,100,000 | 15,300 | 58; 73,300 | |||
| Rauher Busch | Nonsynonymous (P51) | 376 | 16; 12,400,00038 | <0.01 * | 325 | 16; 107,000 | 0.0525 |
| Synonymous (P19) | 1650 | 38; 15,800,000 | 907 | 38; 106,000 | |||
| Bavaria | Nonsynonymous | 679 | 9; 15,500,000 | <0.01 * | 577 | 9; 128,000 | <0.01 * |
| Synonymous | 76,100 | 103; 15,500,000 | 9995 | 103; 15,500,000 | |||
| Haselmühl | Nonsynonymous (HB171) | 528 | 9; 15,500,000 | <0.01 * | 517 | 9; 128,000 | 0.07 |
| Synonymous (303/16) | 437,000 | 103; 10,100,000 | 2110 | 103; 77,700 | |||
| Heselbach | Nonsynonymous (303/16) | 1320 | 86; 11,900 | <0.01 * | 1320 | 86; 11,900 | <0.01 * |
| Synonymous (HB171) | 21,100 | 587; 15,500,000 | 16,900 | 587; 15,500,000 | |||
The lines for the two Federal states are marked by grey shading; the lines showing data from the TBEV-foci within those federal states are left white, An * asterisk marks all statistically significant results.