Figure 1.
Comparison of healing phenotypes, macrophage content, and possible cells that might substitute for macrophages. Several model systems show that wounds can heal well in the absence of or with a reduction in the macrophage population. In many cases, the absence of macrophages might be compensated for by other cell types that can adopt new functions. Artwork is courtesy of Smart Servier Medical Art, freely available at https://smart.servier.com/.