Figure 8.

PyV-Haufen and BKPy-viremia test results during follow-up post diagnostic index biopsy. The degree of “definitive” PyVN decreased with a reduced percentage of tubules expressing SV40-T antigen (follow-up biopsy 1), and disease healed 9.5 months post diagnosis (follow-up biopsy 2). In parallel PyV-Haufen shedding decreased, ceased at time of healing and remained negative thereafter. Conversely, after an initial decrease, BKPy-viremia remained detectable at various levels over an extended period of time; BKPy-viremia levels did not mark PyVN healing.