Table III.

Proportional hazards parameter estimates and hazard ratios (HR) for time to first hemodialysis (HD) catheter failure

Prophylactic treatments	b (SE)	HR	P value
Heparin locking	–2.63 (0.94)	0.07 [0.01-0.45]	.005
Systemic anticoagulation	1.44 (1.23)	4.24 [0.38-47.14]	.240
VTE prophylaxis
5000 U TIDa	–0.72 (0.88)	0.49 [0.09-2.77]	.417
7500 U TIDa	–3.59 (1.65)	0.03 [0.001-0.74]	.032
Patient covariates
Age	–0.02 (0.03)	0.98 [0.92-1.04]	.448
Female sexb	–1.23 (0.90)	0.28 [0.05-1.66]	.284
Comorbidities
HTN	0.53 (0.95)	1.69 [0.26-10.99]	.582
BMI > 40	0.25 (0.76)	1.28 [0.29-5.67]	.746
DM	0.82 (1.12)	2.27 [0.25-20.44]	.464
CKD/ESRD	–1.88 (1.26)	0.15 [0.01-1.80]	.135
COPD	0.20 (1.74)	1.23 [0.26-37.35]	.908
Prehospital anticoagulants	1.24 (1.74)	3.47 [0.34-35.40]	.294
Treatment covariates
Femoral insertionc	3.08 (1.28)	21.65 [1.75-267.65]	.017
Right side	1.66 (1.27)	5.28 [0.44-63.82]	.191

BMI, Body mass index; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; ESRD, end-stage renal disease; HR, hazard ratio; HTN, hypertension; TID, three times per day; VTE, venous thromboembolism.To test for a difference between subcutaneous heparin 5000 TID and 7500 TID, a supplementary model was run using and found no significant difference (b = –2.83; SE = 1.46; HR, 0.06; 95% confidence interval, 0.003-1.04; P = .059).

^aComparison group is no VTE prophylaxis.

^bComparison group is male.

^cComparison group is internal jugular insertion.