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. 2020 Dec 5;73(6):1881–1888.e3. doi: 10.1016/j.jvs.2020.11.033

Supplementary Table II (online only).

Time-varying (nested) model compared with original proportional hazards model for temporary hemodialysis catheter (THDC) failure

Variable Original model
Time-varying model
HR (95% CI) P value HR (95% CI) P value
Heparin locking 0.08 (0.01-0.48) .006 0.35 (0.12-0.99) .049
Systemic anticoagulation 2.46 (0.32-18.91) .388 1.13 (0.34-3.74) .842
VTE prophylaxis
 7500 vs none 0.03 (0.001-0.70) .029 0.11 (0.02-0.68) .018
 7500 vs 5000 0.08 (0.01-1.18) .066 0.48 (0.15-1.54) .213
Age 0.97 (0.92-1.04) .385 0.96 (0.92-1.01) .123
Female 0.25 (0.04-1.61) .144 0.60 (0.20-1.78) .354
HTN 1.48 (0.22-10.00) .685 0.94 (0.27-3.31) .928
BMI > 40 1.75 (0.41-7.49) .452 0.79 (0.23-2.69) .702
DM 2.86 (0.32-25.46) .347 2.65 (0.66-10.71) .172
CKD/ESRD 0.15 (0.01-1.73) .127 0.84 (0.22-3.20) .801
COPD 1.69 (0.29-23.87) .763 3.02 (0.49-18.57) .233
Prehospital anticoagulants 2.64 (0.29-23.87) .388 0.75 (0.20-2.76) .659
Femoral insertion 15.15 (1.63-140.54) .017 5.33 (1.36-20.89) .017
Right side insertion 5.19 (0.44-61.51) .192 1.13 (0.31-4.05) .855

BMI, Body mass index; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; DM, diabetes mellitus; ESRD, end-stage renal disease; HR, hazard ratio; HTN, hypertension; VTE, venous thromboembolism.