Skip to main content
. Author manuscript; available in PMC: 2021 Jan 25.
Published in final edited form as: Neuroimage. 2020 Nov 1;225:117517. doi: 10.1016/j.neuroimage.2020.117517

Fig. 5.

Fig. 5.

Example application of multimodal templates. A series of axial sections with co-registered labelmaps that illustrate applications of the ONPRC18 atlas to scans collected from individual macaques using a variety of neuroimaging contrasts and modalities (DTI, sMRI, PET). Label maps were generated by AntsRegistration software version 2.1; (http://stnava.github.io/ANTs/). (A) DTI scan acquired from one of the individuals in the template after intracranial administration of AAV-HTT (macaque model of Huntington’s Disease) after intrac 6 months. (B, C) sMRI scans (T1w/T2w) that were collected from a juvenile (3yo) Japanese macaque (Macaca fuscata) with a CLN7 mutation (macaque model of Batten disease). (D, E) 18F-Fallypride PET and 18F-FDG PET in a naïve female rhesus macaque. These examples demonstrate some of the potential applications for this atlas, and suggest that it can be a reliable and versatile tool for a wide variety of different kinds of macaque neuroimaging studies.