Antibody responses to SARS-CoV2 in patients with COVID-19 |
Long et al [16]
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n = 285 (63 follow-up measurements for SARS-CoV2 positive hospitalized tested patients)
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“The median day of seroconversion for both IgG and IgM was 13 days post symptom onset”
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“The proportion of patients with positive virus-specific IgG reached 100% approximately 17–19 days after symptom onset, while the proportion of patients with positive virus-specific IgM reached a peak of 94.1% approximately 20–22 days after symptom onset.”
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“Serological testing may be helpful for diagnosis of suspected patients with negative RT-PCR and for the identification of asymptomatic infections.”
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Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 |
Zhao et al [17]
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n = 173 |
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“The presence of antibodies was <40% among patients within 1 week of onset, and rapidly increased to 100.0% (Ab), 94.3% (IgM), and 79.8% (IgG) by day 15 after onset.”
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Antibody detection and dynamic characteristics in patients with COVID-19 |
Xiang et al [18]
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n = 109 (85 with confirmed diagnosis of SARS-CoV2 and 24 patients with suspected diagnosis of SARS-CoV2 infection) |
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“The seroconversion of specific IgM and IgG antibodies were observed as early as the 4th day after symptom onset.”
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“The antibodies against SARS-CoV-2 can be detected in the middle and later stage of the illness.”
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