Table 1.
Pooled sensitivity, pooled specificity and area under the receiver operating characteristic curve (AUROC) of serological tests.
| Types of antibody | Number of studies and samples | Sensitivity with 95% CI (%) | Specificity with 95% CI (%) | AUROC with 95% CI (%) |
|---|---|---|---|---|
| IgM+IgG− | 28 studies, 6161 samples | 6 (4–8) | 99 (98–99) | 0.64 (1.00–0.00) |
| IgG+IgM− | 58 studies, 12,751 samples | 7 (5–11) | 99 (99–99) | 0.91 (1.00–0.00) |
| IgM+IgG+ | 63 studies, 13,344 samples | 53 (46–60) | 100 (99–100) | 0.94 (1.00–0.00) |
| IgM+IgG+/− | 87 studies, 18,924 samples | 68 (62–73) | 98 (97–99) | 0.96 (0.19–1.00) |
| IgG+IgM+/− | 88 studies, 18,597 samples | 73 (69–77) | 99 (98–99) | 0.97 (0.19–1.00) |
| IgM+ or IgG+ | 76 studies, 20,065 samples | 79 (76–83) | 98 (98–99) | 0.97 (0.19–1.00) |
| IgA+ | 6 studies, 934 samples | 78 (67–85) | 88 (82–92) | 0.91 (0.88–0.93) |
CI, confidence interval.