Table 1.
Unmitigated | Mitigated | Suppression 1 | Suppression 2 | |
---|---|---|---|---|
Population-level disease parameters (Ferguson et al8) | ||||
Total deaths∗ | 510, 000 | 255, 000 | 15, 000 | 46, 000 |
ICU bed days† | 7, 130, 158 | 3, 561, 617 | 141, 548 | 385, 326 |
Hospital (non-ICU) bed days‡ | 17, 587, 724 | 8, 785, 321 | 349, 152 | 950, 470 |
Macroeconomic parameters (Keogh-Brown et al9) | ||||
1-year national income loss (%) | 1.84% | 2.75% | 6.05% | 6.05% |
Workforce unemployed (%)§ | 34% | |||
Weeks of unemployment§,‖ | 1 | 4 | 62 | 57 |
Patient-level QALY loss and costed resource use parameters | ||||
Average QALY loss due to COVID-19 death | 8.79882 | |||
Average QALY loss for ICU bed day | 0.00110 | |||
Average QALY loss for hospital (non-ICU) bed day | 0.00002 | |||
Average QALY loss due to unemployment (per week)§ | 0.00161 | |||
Average cost for ICU bed day | £1,152 | |||
Average cost for hospital (non-ICU) bed day | £933 | |||
Average (to death) healthcare saving due to COVID-19 death | £25, 544 | |||
Average cost for end-of-life care§ | £232 |
AUC indicates area under the curve; COVID-19, coronavirus disease 2019; ICU, intensive care unit; QALY, quality-adjusted life-years.
For unmitigated and mitigated total deaths as reported in text. For both suppression strategies taken from Table 5.
For unmitigated and mitigated calculated using AUCs in Figure 2. For suppression 1 AUC in Figure 4 gives deaths for R0 = 2.2 and so converted to R0 = 2.4 using peak ICU bed numbers in Table 4 and assuming proportionality between total ICU bed days and ICU peaks.
Calculated using Ferguson assumptions: 30% of those hospitalized need critical care (CC); CC patients have 10 ICU + 6 non-ICU bed days; other patients hospitalized have 8 non-ICU bed days.
For scenario analyses only.