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. 2020 Aug 27;23(11):1432–1437. doi: 10.1016/j.jval.2020.07.001

Table 1.

Summary of input parameters.

Unmitigated Mitigated Suppression 1 Suppression 2
Population-level disease parameters (Ferguson et al8)
Total deaths 510, 000 255, 000 15, 000 46, 000
ICU bed days 7, 130, 158 3, 561, 617 141, 548 385, 326
Hospital (non-ICU) bed days 17, 587, 724 8, 785, 321 349, 152 950, 470
Macroeconomic parameters (Keogh-Brown et al9)
1-year national income loss (%) 1.84% 2.75% 6.05% 6.05%
Workforce unemployed (%)§ 34%
Weeks of unemployment§, 1 4 62 57
Patient-level QALY loss and costed resource use parameters
Average QALY loss due to COVID-19 death 8.79882
Average QALY loss for ICU bed day 0.00110
Average QALY loss for hospital (non-ICU) bed day 0.00002
Average QALY loss due to unemployment (per week)§ 0.00161
Average cost for ICU bed day £1,152
Average cost for hospital (non-ICU) bed day £933
Average (to death) healthcare saving due to COVID-19 death £25, 544
Average cost for end-of-life care§ £232

AUC indicates area under the curve; COVID-19, coronavirus disease 2019; ICU, intensive care unit; QALY, quality-adjusted life-years.

For unmitigated and mitigated total deaths as reported in text. For both suppression strategies taken from Table 5.

For unmitigated and mitigated calculated using AUCs in Figure 2. For suppression 1 AUC in Figure 4 gives deaths for R0 = 2.2 and so converted to R0 = 2.4 using peak ICU bed numbers in Table 4 and assuming proportionality between total ICU bed days and ICU peaks.

Calculated using Ferguson assumptions: 30% of those hospitalized need critical care (CC); CC patients have 10 ICU + 6 non-ICU bed days; other patients hospitalized have 8 non-ICU bed days.

§

For scenario analyses only.

1 and 4 weeks are taken from Keogh-Brown et al9 but 62 and 57 weeks based on % of time with social distancing in place reported in Table 4 of Ferguson et al.8