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. 2021 Jan 13;13(1):1859813. doi: 10.1080/19490976.2020.1859813

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© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — In vitro gastric digestion model showing stability profiles of SIgA1 and SIgA2 produced in CHO cells and Nicotiana benthamiana. Comparison of cfaE-antigen binding for anti-cfaE mAbs (SIgA1 and SIgA2) after incubation in an in vitro gastric digestion model as measured by ELISA. The SIgA mAbs were produced in (a) CHO cells, (b) WT, and (c) ΔXF N. benthamiana. The relative percent of cfaE antigen binding remaining for each mAb was normalized to time zero binding. Each data point is displayed as the mean ± the data range; n = 2