Table 1.
B-cell epitopes |
T-cell epitopes |
|||
---|---|---|---|---|
Epitope | Position | Epitope | Position | Most probable binding HLA |
MHC-I binding | ||||
VFLLVTLAIL | 25–34 | LTALRLCAY (T1) | 34–42 | HLA-A*01:01 (PDB ID: 6AT9_A) |
ILTALRLCAY | 33–42 | VSLVKPSFY (T2) | 49–57 | HLA-A*30:02 (PDB ID: 6J2A_A) |
LLFLAFVVFL | 18–37 | MHC-II binding (Best epitope) | ||
LAFVVFLLVTLAILT (T3) (Core peptide: VFLLVTLAI) | 21–35 | HLA-DRB1:15:01 (PDB ID: 5V4M_C,F,I,L) |
The epitope positions were found to be same for the SARS-CoV2 E-protein and consensus E-protein.