Table 2.
Inflammatory mediators at hospital discharge as well as clinical outcomes of the study cohort stratified by Favipiravir.
| Variable, median (IQR) unless specified otherwise | All (N = 89) | Favipiravir |
p-value | |
|---|---|---|---|---|
| No (n = 45) | Yes (n = 44) | |||
| Inflammatory parameters | ||||
| CRP, mg/dL [69/89] | 41 (14−98) | 33 (14−79) | 50 (14−130) | 0.413 |
| Ferritin, μg/L [53/89] | 1055 (439−1454) | 993 (295−1650) | 1107 (539−1404) | 0.968 |
| LDH, U/L [49/89] | 380 (339−484) | 366 (338−427) | 452 (351−554) | 0.259 |
| IL-6, pg/mL [26/89] | 143 (44−547) | 143 (113−478) | 138 (25−742) | 0.410 |
| LOS, days [87/89] | 7 (4−11) | 7 (3−11) | 7 (4−12) | 0.948 |
| Outcomes, n (%) | ||||
| Transferred to ICU | 16 (18.0 %) | 8 (17.8 %) | 8 (18.2 %) | 0.960 |
| Discharged home | 60 (67.4 %) | 31 (68.9 %) | 29 (65.9 %) | 0.764 |
| SaO2 on discharge | 94 (93−96) | 95 (93−96) | 94 (93−96) | 0.324 |
| Died | 11 (12.4 %) | 6 (13.3 %) | 5 (11.4 %) | 0.778 |
IQR = interquartile range; CRP = C-reactive protein; LDH = lactate dehydrogenase; IL-6 = interleukin 6; LOS = length of hospital stay; ICU = intensive care unit; SaO2 = oxygen saturation (%).