Table 3.
Cross reaction between several common coronaviruses and pathogens on N protein & S protein test strips. (Ct, cycle threshold; TCID50, median tissue culture infective dose; CFU, colony formation unit; EID50, egg infectious dose).
| Samples (Viruses and bacteria) |
Ct/titer/CFU/ug | N- strips results | S- strips results | |
|---|---|---|---|---|
| HCoV-229E | Ct 27 | – | – | |
| HCoV-OC43 | Ct 25 | – | + | |
| HCoV-NL63 | Ct 23 | – | + | |
| HCoV-HKU1 | Ct 25 | – | + | |
| influenza A H1N1 | 1.22 × 104 TCID50/mL | – | – | |
| influenza A H3N2 | 1.25 × 104 TCID50/mL | – | – | |
| influenza A H5N1 | 5.25 × 104 TCID50/mL | – | – | |
| influenza A H7N9 | 1.00 × 104 TCID50/mL | – | – | |
| influenza A H9N2 | 1.25 × 104 TCID50/mL | – | – | |
| influenza B Victoria strain | 1.00 × 104 TCID50/mL | – | – | |
| influenza B Yamagata strain | 1.00 × 104TCID50/mL | – | – | |
| Measles virus | 1 × 104 TCID50/mL | – | – | |
| Mumps virus | 1 × 104 TCID50/mL | – | – | |
| Rubella virus | 1 × 104 TCID50/mL | – | – | |
| Varicella zoster virus | 1 × 104 TCID50/mL | – | – | |
| Staphylococcus aureus | 2.3 × 107 CFU/mL | – | – | |
| Pseudomonas aeruginosa | 1.8 × 107 CFU/mL | – | – | |
| SARS-CoV N protein | 2 μg/mL | + | – | |
| MERS-CoV N protein | 2 μg/mL | – | – | |
| Chicken IBV | 1 × 104 EID50/mL | – | – | |