Table 2.
Potential bioactive compounds against corona viruses and their mechanisms of action.
Bioactive compound | Plant | Mechanism of action | References |
---|---|---|---|
Celastrol | Triterygium regelii | Inhibits 3CLpro | Ryu et al. (2010) |
Tingenone | Triterygium regelii | Inhibits 3CLpro | Ryu et al. (2010) |
Pristimererin | Triterygium regelii | Inhibits 3CLpro | Ryu et al. (2010) |
Iguesterin | Triterygium regelii | Inhibits 3CLpro | Ryu et al. (2010) |
Tanshinones I–VII | Salvia miltiorrhiz | Inhibits PLpro | Park et al. (2012b) |
Hirsutenone | Alnus japonica | Inhibits PLpro | (Park et al., 2012a, 2012b) |
Emodin | Rheum palmatum | Blocks the interaction of S protein and ACE2 | Ho et al. (2007) |
Ginsenoside-Rb1 | Panax ginseng | Blocks glycoprotein | Wu et al. (2004) |
Aescin | Aesculus hippocastanum | unknown | Wu et al. (2004) |
Leptodactylone | Boenninghausenia sessilica | unknown | Yang et al. (2007) |
Lycorine | Lycoris radiate | unknown | Li et al. (2005a) |
Reserpine | Rauvolfia serpentina | unknown | Wu et al. (2004) |
Dihydrotanshinone | Salvia miltiorrhiza | unknown | Kim et al. (2018) |
Resveratrol | Polygonum cuspidatum | unknown | Lin et al. (2017) |
Oolonghomobisflavan-A | Tea plant | Inhibits Mpro | Bhardwaj et al. (2020) |
Cepharanthine | Stephania japonica | Blocks ACE2 | Fan et al. (2020) |