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. 2020 Jul 31;885:173450. doi: 10.1016/j.ejphar.2020.173450

Table 2.

Potential bioactive compounds against corona viruses and their mechanisms of action.

Bioactive compound Plant Mechanism of action References
Celastrol Triterygium regelii Inhibits 3CLpro Ryu et al. (2010)
Tingenone Triterygium regelii Inhibits 3CLpro Ryu et al. (2010)
Pristimererin Triterygium regelii Inhibits 3CLpro Ryu et al. (2010)
Iguesterin Triterygium regelii Inhibits 3CLpro Ryu et al. (2010)
Tanshinones I–VII Salvia miltiorrhiz Inhibits PLpro Park et al. (2012b)
Hirsutenone Alnus japonica Inhibits PLpro (Park et al., 2012a, 2012b)
Emodin Rheum palmatum Blocks the interaction of S protein and ACE2 Ho et al. (2007)
Ginsenoside-Rb1 Panax ginseng Blocks glycoprotein Wu et al. (2004)
Aescin Aesculus hippocastanum unknown Wu et al. (2004)
Leptodactylone Boenninghausenia sessilica unknown Yang et al. (2007)
Lycorine Lycoris radiate unknown Li et al. (2005a)
Reserpine Rauvolfia serpentina unknown Wu et al. (2004)
Dihydrotanshinone Salvia miltiorrhiza unknown Kim et al. (2018)
Resveratrol Polygonum cuspidatum unknown Lin et al. (2017)
Oolonghomobisflavan-A Tea plant Inhibits Mpro Bhardwaj et al. (2020)
Cepharanthine Stephania japonica Blocks ACE2 Fan et al. (2020)