The decrease of the YAP protein level caused by proteasome activity
(a,b): MDA-MB-231 and SUM149 cells with (shHMGA2) or without (shControl) HMGA2 knockdown were treated with MG132 (20μM) or DMSO for 4 h.MG132 treatment prevented the decrease in the YAP protein level induced by HMGA2shRNA. (c,d): Cells were divided into the DMSO-treated group and MG132-treated group, and the YAP protein level in Hsh cells relative to that in Csh cells was calculated for each group. The graphs panels were shown. (*P<.05, **P<.01, ***P<.001)