Table 1.
Patients | Hospital unit | Extracutaneous manifestations related to COVID-19 | Cutaneous manifestations occurring concomitantly to COVID-19 | Delay between first COVID-19 extracutaneous symptoms and rash onset (days) | Drugs used before the occurrence of the rash | Delay between initiation of each treatments and the onset of the rash (days) | Hypereosinophilia (>0,5G/L) |
---|---|---|---|---|---|---|---|
Patient 1 | ICU | Severe bilateral pneumonia requiring orotracheal intubation | Maculopapular exanthema of trunk and shoulders | 25 | Ceftriaxone Azithromycine Hydroxychloroquine |
25 | Yes |
Tazocilline Linézolide Valaciclovir |
20 | ||||||
Patient 2 | ICU | Severe bilateral pneumonia requiring oxygen therapy | Diffuse maculopapular exanthema | 20 | Amoxicilline/clavulanic acid | 20 | No |
Ceftriaxone Spiramycine Azithromycine Hydroxychloroquine |
3 | ||||||
Patient 3 | CMU | Flu-like symptoms | Maculopapular exanthema of abdomen and limbs and bilateral livedo of knees Pruritus | 5 | Paracetamol | 0 | No |
Patient 4 | CMU | Flu-like symptoms | Maculopapular exanthema of trunk and limbs with slight pruritus | 30 | Ceftriaxone Azithromycine |
30 | Yes |
Patient 5 | ICU | Severe bilateral pneumonia requiring orotracheal intubation | Maculopapular exanthema of trunk and limbs | 35 | Ceftriaxone Azithromycine Linézolide |
35 | No |
Tazocilline Aciclovir |
25 | ||||||
Patient 6 | ICU | Severe bilateral pneumonia requiring oxygen therapy | Diffuse maculopapular exanthema Pruritus |
30 | Ceftriaxone Spiramycine Hydroxychloroquine |
20 | Yes |
Tazocilline Linézolide |
5 |
ICU, intensive care unit; CMU, conventional medicine unit; COVID-19, coronavirus disease 2019.