Table 2.

Nucleotide and amino acid mutations in the genomes of SARS-CoV-2 variants described in this study as compared to the Wuhan NC_045512.2 variant.

Genome region	Encoded protein	Nucleotide position	Wuhan, China NC_045512.2	Moscow, Russia EPI_ISL_428851		Moscow, Russia EPI_ISL_428852
			NT	NT	AA	NT	AA
5′UTR	–	241	C	T	N/A	T	N/A
ORF1ab	nsp3 (PLPro)	3037	C	T	Phe924	T	Phe924
		3373	C	A	Asp1036→Glu	C	–
	nsp5 (3CLPro)	10,969	C	C	–	T	Phe3568
	nsp12 (RdRP)	14,408	C	T	Pro4715→Leu	T	Pro4715→Leu
ORF2	S	23,403	A	G	Asp614→Gly	G	Asp614→Gly
ORF9a	N	28,881	G	A	Arg203→Lys	A	Arg203→Lys
		28,882	G	A		A
		28,883	G	C	Gly204→Arg	C	Gly204→Arg

SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; N/A - not applicable.