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. 2021 Jan 9;15(3):409–416. doi: 10.1016/j.pcd.2021.01.002

Table 1.

Antidiabetic agents in hospitalized patients with type 2 diabetes and COVID-19 [53].

Hospitalized moderate disease Hospitalized severe disease (ICU patients)
Recommended ✓ Insulin ✓ Insulin
✓ DPP4 inhibitor ✓ DPP4 inhibitor
✓ GLP-1 analogues
✓ Metformin
Not recommended ✓ Thiazolidinedione ✓ Thiazolidinedione
✓ SGLT2 inhibitors ✓ SGLT2 inhibitors
✓ Sulfonylurea
Use with caution ✓ Sulfonylurea ✓ Metformin
✓ α-Glucosidase inhibitors ✓ α-Glucosidase inhibitors
✓ GLP-1 analogues

[DPP4: Dipeptidyl peptidase-4, SGLT2: Sodium glucose transporter 2, GLP-1: Glucagon-like peptide-1].