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. 2021 Jan 6;117:154703. doi: 10.1016/j.metabol.2021.154703

Table 3.

Univariate and multivariate logistic regression analyses for serious events (model 1).a

Univariate
Multivariate
Odds ratio (95% CI) p Odds ratio (95% CI) p
Excess body weight, BMI ≥ 25 kg/m2 3.78 (1.04–13.72) 0.04 5.58 (1.30–23.96) 0.02
Age, years 0.98 (0.95–1.01) 0.17 0.98 (0.94–1.02) 0.35
Sex 1.48 (0.57–3.80) 0.42 1.76 (0.61–5.09) 0.30
Type 2 diabetes 0.66 (0.20–2.14) 0.49 0.99 (0.21–4.77) 0.99
Arterial hypertension 0.75 (0.29–1.90) 0.54 0.93 (0.21–4.10) 0.92
Chronic respiratory diseaseb 1.42 (0.27–7.55) 0.68 1.68 (0.23–12.33) 0.61
RAAS inhibitors 0.76 (0.27–2.15) 0.61 1.25 (0.24–6.34) 0.79
Statins 0.29 (0.04–2.31) 0.24 0.14 (0.01–1.74) 0.13
HCQ/AZT treatment combinationc 0.73 (0.23–2.25) 0.58 0.33 (0.08–1.35) 0.12

Abbreviations: AZT = azithromycin. BMI = body mass index. HCQ = hydroxychloroquine. RAAS = renin-angiotensin-aldosterone system.

Bold value is statistically significant to p-value < 0.05.

a

Univariate and multivariate associations between serious events and BMI between 18.5 and 25 kg/m2 (reference), BMI ≥ 25 kg/m2, age, sex, type 2 diabetes, arterial hypertension, chronic respiratory disease, RAAS inhibitors, statins and HCQ/AZT combination.

b

Chronic respiratory disease: asthma, obstructive sleep apnea, chronic obstructive pulmonary disease.

c

HCQ/AZT: combination of hydroxychloroquine for 10 days and azithromycin for 5 days.