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. 2020 Dec 21;2:100015. doi: 10.1016/j.lanepe.2020.100015

Table 2b.

Factors associated with SARS-CoV-2 IgG and Neutralising antibody positivity in Visit 2.

Variable IgG Antibody positivity (Visit 2)
Neutralising Antibody positivity (Visit 2)
Risk RR (95% CI) Risk Difference (95% CI) Risk RR (95% CI) Risk Difference (95% CI)
Gender
 Female 5/37 (14%) 1.1 (0.4 to 2.6) 0.007 (-0.1 to 0.1) 2/6 (33%) 0.7 (0.2 to 2.2) -0.2 (-0.6 to 0.3)
 Male 20/156 (13%) Baseline 11/22 (50%) Baseline
Shared Bedroom
 Yes 7/87 (8%) 0.5 (0.2 to 1.0) -0.09 (-0.2 to -0.003) 5/8 (63%) 1.6 (0.7 to 3.3) 0.23 (-0.2 to 0.6)
 No 18/102 (18%) Baseline 8/20 (40%) Baseline
Shared Bathroom
 Yes 22/172 (13%) 0.9 (0.3 to 2.7) -0.01 (-0.2 to 0.1) 11/24 (46%) 0.9 (0.3 to 2.7) -0.04 (-0.6 to 0.5)
 No 3/21 (14%) Baseline 2/4 (50%) Baseline
Bathroom shared with one other Army Colleague
 Yes 16/72 (22%) 2.9 (1.3 to 6.2) 0.2 (0.04 to 0.3) 8/17 (47%) 1 (0.5 to 2.4) 0.02 (-0.4 to 0.4)
 No 9/117 (8%) Baseline 5/11 (45%) Baseline
Smoke or Vape (limited data available)
 Yes 3/8 (38%) 0.5 (0.2-1.2) -0.4(-0.8 to -0.1) 0/3 NA -0.7 (-0.9 to -0.5)
 No 17/21 (81%) Baseline 12/17 (71%) Baseline
Asymptomatic cases by gender
 Asymptomatic Female 5/29 (17%) 2.1 (0.8 to 5.7) 0.1 (-0.6 to 0.2) 2/6 (33%) 0.6 (0.2 to 2.1) -0.2 (-0.7 to 0.3)
 Asymptomatic Male 9/109 (8%) Baseline 6/11 (55%) Baseline
Symptomatic cases by gender
 Symptomatic Female 0/8 (0%) NA -0.2 (-0.4 to -0.1) 0/0 NA NA
 Symptomatic Male 11/47 (23%) Baseline 5/11 (45%) Baseline
Close contact with a confirmed case
 Yes 5/5 (100%) 9.4 (6.2 to 14.2) 0.9 (0.8 to 0.94) 3/5 (60%) 1.4 (0.6 to 3.2) 0.17 (-0.3 to 0.6)
 No 20/188 (11%) Baseline 10/23 (43%) Baseline
Symptom Variable IgG Antibody positivity
Neutralising Antibody positivity
Risk RR (95% CI) Risk Difference (95% CI) Risk RR (95% CI) Risk Difference (95% CI)
Any Symptoms
 Yes 11/55 (20%) 1.98 (0.96 to 4.1) 0.1 (-0.02 to 0.2) 5/11 (45%) 0.97 (0.4 to 2.2) -0.02 (-0.4 to 0.4)
 No 14/138 (10%) Baseline 8/17 (47%) Baseline
Fever
 Yes 6/20 (30%) 2.7 (1.2 to 6.0) 0.2 (-0.02 to 0.4) 4/6 (67%) 1.6 (0.8 to 3.5) 0.3 (-0.2 to 0.7)
 No 19/173 (11%) Baseline 9/22 (40%) Baseline
Cough
 Yes 9/33 (27%) 2.7 (1.3 to 5.6) 0.2 (0.1 to 0.3) 4/9 (44%) 0.9 (0.4 to 2.2) -0.03 (-0.4 to 0.4)
 No 16/160 (10%) Baseline 9/19 (47%) Baseline
Anosmia (Loss of Smell)
 Yes 2/5 (40%) 3.3 (1.0 to 10.2) 0.3 (-0.2 to 0.7) 0/2 (0%) _ -0.5 (-0.7 to -0.3)
 No 23/188 (12%) Baseline 13/26 (50%) Baseline
Ageusia (Loss of Taste)
 Yes 3/4 (75%) 6.4 (3.2 to 12.8) 0.6 (0.2 to 1.1) 1/3 (33%) 0.7 (0.1 to 3.6) -0.1 (-0.7 to 0.4)
 No 22/189 (12%) Baseline 12/25 (48%) Baseline

Army/civilian/family status is not included as the results are confounded by the transmission dynamics of the virus through the barracks with civilians most likely to have recent infection and Army personnel with previous infection.