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. 2020 Dec 29;176:112920. doi: 10.1016/j.bios.2020.112920

Fig. 2.

Fig. 2

The dynamics of anti-SARS-CoV-2 antibody binding onto immobilized SARS-CoV-2-nucleoprotein antigen, measuring by SD-PSI in real-time. (A) The schematic diagram showing the binding between antibody and antigen, a) in continuous reciprocating-flowing and b) in static system. (B) Sensorgram obtained from the binding of anti-SARS-CoV-2 nucleoprotein (434.0 ng/mL) to nucleoprotein antigen of SARS-CoV-2 in a) reciprocating-flowing and b) static system, upper: measuring in real-time from 0 s to 1200 s, below: measuring in real-time from 100 s to 350 s. (C) Sensorgram obtained from the binding of anti-SARS-CoV-2 nucleoprotein (4.34 ng/mL) to nucleoprotein antigen of SARS-CoV-2 in a) reciprocating-flowing and b) static system, upper: measuring in real-time from 0 s to 3100 s, below: measuring in real-time from 0 s to 650 s. (D) The first order derivative of the fitting curves taken from the dynamics curves for 434.0 ng/mL antibody solution. (E) The first order derivative of the fitting curves taken from the dynamics curves for 4.34 ng/mL antibody solution.